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Through our clinical trials program, patients who qualify can access other health care alternatives and investigational new drugs long before they are available on the open market. The Manderson Cancer Center jointly conducts clinical research with MD Anderson Cancer Center.

Lewis & Faye Manderson Cancer Center at DCH Regional Medical Center is a National Cancer Institute (NCI) Central Institutional Review Board Signatory Institution.  We are also an affiliate member of NRG Oncology which brings together the unique and complementary research areas of the National Surgical Adjuvant Breast and Bowel Project (NSABP), the Radiation Therapy Oncology Group (RTOG), and the Gynecologic Oncology Group (GOG). NRG Oncology builds upon their more than 150 years of cumulative research experience to conduct practice defining, multi-institutional clinical trials resulting in the improved survival and quality of life of patients with cancer. NRG Oncology has been awarded a grant by the National Cancer Institute (NCI) as a member of the NCI National Clinical Trials Network (NCTN).

During the months of January through December 2017, a total of 98 patents were accrued to trials.
Treatment/Interventional Trials - 9 onsite
Diagnostic Trials - 48 onsite
Prevention and Control Research - 39 onsite
Patient Registry Studies - 2 (offsite referrals) is a searchable database which provides patients, family members and the public with information about current ongoing clinical research studies.

For any questions or to learn if you quality for a trial, please contact our Clinical Research Coordinator, Danielle Daniel, by phone at (205) 759-6237 or by email at

Below is a list of clinical trials that are currently offered at Manderson Cancer Center. We have attached the link for each study for ease in finding detailed information regarding these studies.

NRG Oncology

NRG-GU005 - Stereotactic Body Radiation Therapy or Intensity-Modulated Radiation Therapy in Treating Patients With Stage IIA-B Prostate Cancer

This randomized phase III trial studies how well stereotactic body radiation therapy works compared to intensity-modulated radiation therapy in treating patients with stage IIA-B prostate cancer. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Stereotactic body radiation therapy is a specialized radiation therapy that sends x-rays directly to the tumor using smaller doses over several days and may cause less damage to normal tissue. Stereotactic body radiation therapy may work better in treating patients with prostate cancer.

MD Anderson Research Studies

2013-0609 – Biospecimen Banking and Biomarker Validation for Lung Cancer Early Detection in Cohort Receiving Low Dose Helical Computed Tomography Screening

This is a multicenter study led by MD Anderson to establish a Biospecimen repository from a cohort of current and former smokers who meet the criteria for low dose helical tomography (LDCT) screening.

At MD Anderson, they are developing new tests that may help improve lung cancer screening results. The Manderson Cancer Center is collaborating with MD Anderson in the Lung Cancer Early Detection Study. Click here for details.

Lung Cancer Studies

INSIGHT – An Observational Study Assessing the Clinical Effectiveness of Veristrat® and Validating Immunotherapy Tests in Subjects with Non-Small Cell Lung Cancer

The primary purpose of this study is to assess the physician’s clinical practice patterns while using Veristrat in subjects with non-small cell lung cancer whose tumors are epidermal growth factor receptor (EGFR) wild-type or EGFR negative.

Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Connect MDS and AML:  The Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry

The purpose of this study is to observe and collect data for people with Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)


National Breast Cancer and Lymphedema Registry

This registry will provide documented support for the potential importance of pre-emptive strategies for breast cancer-associated lymphedema

Newly Diagnosed Cancer Patients

Real-time Associations Between Mood and Behavior

This study is important to evaluate the value of being active while being treated for cancer. The results of this study will help doctors and nurses understand better ways to help individuals with cancer who are receiving treatment.