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Through our clinical trials program, patients who qualify can access other health care alternatives and investigational new drugs long before they are available on the open market. The Manderson Cancer Center jointly conducts clinical research with MD Anderson Cancer Center.

Lewis & Faye Manderson Cancer Center at DCH Regional Medical Center has recently been approved as a National Cancer Institute (NCI) Central Institutional Review Board Signatory Institution.  We are also an affiliate member of NRG Oncology which brings together the unique and complementary research areas of the National Surgical Adjuvant Breast and Bowel Project (NSABP), the Radiation Therapy Oncology Group (RTOG), and the Gynecologic Oncology Group (GOG). NRG Oncology builds upon their more than 150 years of cumulative research experience to conduct practice defining, multi-institutional clinical trials resulting in the improved survival and quality of life of patients with cancer. NRG Oncology has been awarded a grant by the National Cancer Institute (NCI) as a member of the NCI National Clinical Trials Network (NCTN).

ClinicalTrials.gov is a searchable database which provides patients, family members and the public with information about current ongoing clinical research studies.

Below is a list of clinical trials that are currently offered at Manderson Cancer Center. We have attached the link for each study for ease in finding detailed information regarding these studies.

For any questions or to learn if you quality for a trial, please contact our Clinical Research Coordinator, Danielle Daniel, by phone at (205) 759-6237 or by email at cancer.research@dchsystem.com.

NRG Oncology

NRG-CC001: A Randomized Phase III Trial of Memantine and Whole Brain Radiotherapy with or without Hippocampal Avoidance in Patients with Brain Metastases

https://clinicaltrials.gov/ct2/show/NCT02360215

This study compares memantine hydrochloride and whole-brain radiotherapy with or without hippocampal avoidance in reducing neurocognitive decline in patients with cancer that has spread from the primary site (place where it started) to the brain.

NRG-CC003 – A Randomized Phase II/III Trial of Prophylactic Cranial Irradiation with or without Hippocampal Avoidance for Small Cell Lung Cancer

https://clinicaltrials.gov/ct2/show/NCT02635009

This trial studies how well whole-brain radiation therapy works and compares it with or without hippocampal avoidance in treating patients with small cell lung cancer.

MD Anderson Research Studies

2013-0609 – Biospecimen Banking and Biomarker Validation for Lung Cancer Early Detection in Cohort Receiving Low Dose Helical Computed Tomography Screening

This is a multicenter study led by MD Anderson to establish a Biospecimen repository from a cohort of current and former smokers who meet the criteria for low dose helical tomography (LDCT) screening.

Non-small Cell Lung Cancer (NSCLC)

INSIGHT – An Observational Study Assessing the Clinical Effectiveness of Veristrat® and Validating Immunotherapy Tests in Subjects with Non-Small Cell Lung Cancer

The primary purpose of this study is to assess the physician’s clinical practice patterns while using Veristrat in subjects with non-small cell lung cancer whose tumors are epidermal growth factor receptor (EGFR) wild-type or EGFR negative.

Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML)

Connect MDS and AML:  The Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) Disease Registry

https://clinicaltrials.gov/show/NCT01688011

The purpose of this study is to observe and collect data for people with Myelodysplastic Syndromes (MDS) or Acute Myeloid Leukemia (AML)

Breast

National Breast Cancer and Lymphedema Registry

https://clinicaltrials.gov/show/NCT01580800

This registry will provide documented support for the potential importance of pre-emptive strategies for breast cancer-associated lymphedema

Paroxysmal Nocturnal Hemoglobinuria (PNH)

PNH Registry: Paroxysmal Nocturnal Hemoglobinuria Registry

https://clinicaltrials.gov/show/NCT01374360

This Registry is a non-interventional study that has been designed to capture safety and effectiveness data for Soliris®, as well as to compile data on the natural history and management of patients with PNH.